Intrinsic Properties of Mouse Lumbar Motoneurons 2 Revealed by Intracellular Recording in Vivo
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چکیده
s; no of words: 237 13 Number of figures: 8; number of tables: 2 14 Correspondence to: 15 Claire Meehan 16 University of Copenhagen, 17 Department of Neuroscience and Pharmacology 18 Panum Institute, bldg 18.5 19 Blegdamsvej 3 2
منابع مشابه
Intrinsic properties of mouse lumbar motoneurons revealed by intracellular recording in vivo.
We have developed an in vivo model for intracellular recording in the adult anesthetized mouse using sharp microelectrode electrodes as a basis for investigations of motoneuron properties in transgenic mouse strains. We demonstrate that it is possible to record postsynaptic potentials underlying identified circuits in the spinal cord. Forty-one motoneurons with antidromic spike potentials (>50 ...
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Mitra P, Brownstone RM. An in vitro spinal cord slice preparation for recording from lumbar motoneurons of the adult mouse. J Neurophysiol 107: 728–741, 2012. First published October 26, 2011; doi:10.1152/jn.00558.2011.—The development of central nervous system slice preparations for electrophysiological studies has led to an explosion of knowledge of neuronal properties in health and disease. ...
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Hypocretinergic (orexinergic) neurons in the lateral hypothalamus project to motor columns in the lumbar spinal cord. Consequently, we sought to determine whether the hypocretinergic system modulates the electrical activity of motoneurons. Using in vivo intracellular recording techniques, we examined the response of spinal motoneurons in the cat to electrical stimulation of the lateral hypothal...
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The present study was undertaken 1) to examine the neuronal mechanisms responsible for the inhibition of spinal cord motoneurons that occurs in alpha-chloralose-anesthetized cats following the microinjection of carbachol into the nucleus pontis oralis (NPO), and 2) to determine whether the inhibitory mechanisms are the same as those that are responsible for the postsynaptic inhibition of motone...
متن کاملAn in vitro spinal cord slice preparation for recording from lumbar motoneurons of the adult mouse.
The development of central nervous system slice preparations for electrophysiological studies has led to an explosion of knowledge of neuronal properties in health and disease. Studies of spinal motoneurons in these preparations, however, have been largely limited to the early postnatal period, as adult motoneurons are vulnerable to the insults sustained by the preparation. We therefore sought ...
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